The three-dimensional porous structure of the hydrogels will increase the surface area of the material, accordingly allowing more recognition elements to be immobilized. Their large surface area structures offer sufficient space to place particles, functional groups, dyes, and so on, which could apply numerous functionalities. If the probes are entrapped within the matrix or on top of the matrix, they are easily stored in a soft and flexible hydrogel network, as a result, are much less affected by surface interactions, and can preserve their activity. another incredible feature of hydrogels as an immobilizing matrix is the reduction or even prevention of nonspecific binding. because of the hydrophilicity of polymers utilized in hydrogels, nonspecific binding is notably decreased The flexible nature of hydrogels also can be used to increase access to probes. the rough but elastic surfaces increase surface bonding ability in addition to enhancing the exposure of the recognition site [364, 365]. various hydrogels with biosensing abilities were recognized. The most regularly used hydrogels are polyvinyl alcohol, polyethylene glycol, polyacrylate families, and electroconductive hydrogels.
The three-dimensional porous structure of the hydrogels will increase the
surface
area of the material,
accordingly
allowing more recognition elements to
be immobilized
. Their large
surface
area structures offer sufficient space to place particles, functional groups, dyes, and
so
on, which could apply numerous functionalities. If the probes
are entrapped
within the matrix or on top of the matrix, they are
easily
stored in a soft and flexible hydrogel network,
as a result
, are much less
affected
by
surface
interactions, and can preserve their activity.
another
incredible feature of hydrogels as an immobilizing matrix is the reduction or even prevention of nonspecific binding.
because
of the hydrophilicity of polymers utilized in hydrogels, nonspecific binding is
notably
decreased The flexible nature of hydrogels
also
can be
used
to increase access to probes.
the
rough
but
elastic
surfaces
increase
surface
bonding ability
in addition
to enhancing the exposure of the recognition site [364, 365].
various
hydrogels with
biosensing
abilities
were recognized
. The most
regularly
used
hydrogels are polyvinyl alcohol, polyethylene glycol,
polyacrylate
families, and
electroconductive
hydrogels.