The evidence behind the regenerative treatment
The evidence behind the regenerative treatment My1bo
Periodontal disease is a broad term that refers to various disorders affecting the gingiva, supporting connective tissue and alveolar bone that hold the teeth in place in the jaws (Williams, 1990). The furcation area is one of the challenging sites with significant clinical and therapeutic implications, and it represents, if involved, a high impacting risk factor at the tooth and site level (Leknes et al. , 1994) as well as a critical aspect in the determination of the tooth prognosis (Bower, 1979a). It is defined as the bifurcation and trifurcation invasion of multirooted teeth (Periodontology, 2001). During chronic inflammation, the progression of periodontal disease may affect the multirooted teeth (Sanz et al. , 2015). There are several treatment options in cases with furcation involvement. Regeneration is one of those, but it requires very careful preliminary considerations to get the expected outcomes (Bowers et al. , 2003). 
Periodontal disease is a broad term that refers to various disorders affecting the  
gingiva
, supporting connective tissue and alveolar bone that hold the teeth in place in the jaws (Williams, 1990). The  
furcation
 area is one of the challenging sites with significant clinical and therapeutic implications, and it represents, if involved, a high impacting  
risk
 factor at the tooth and site level ( 
Leknes
 et al. 
 ,
 1994)  
as well
 as a critical aspect in the determination of the tooth prognosis (Bower, 1979a). It  
is defined
 as the bifurcation and  
trifurcation
 invasion of  
multirooted
 teeth ( 
Periodontology
, 2001). During chronic inflammation, the progression of periodontal disease may affect the  
multirooted
 teeth ( 
Sanz
 et al. 
 ,
 2015). There are several treatment options in cases with  
furcation
 involvement. Regeneration is one of those,  
but
 it requires  
very
 careful preliminary considerations to  
get
 the  
expected
 outcomes (Bowers et al. 
 ,
 2003).