The evidence behind the regenerative treatment

Periodontal disease is a broad term that refers to various disorders affecting the gingiva, supporting connective tissue and alveolar bone that hold the teeth in place in the jaws (Williams, 1990). The furcation area is one of the challenging sites with significant clinical and therapeutic implications, and it represents, if involved, a high impacting risk factor at the tooth and site level (Leknes et al. , 1994) as well as a critical aspect in the determination of the tooth prognosis (Bower, 1979a). It is defined as the bifurcation and trifurcation invasion of multirooted teeth (Periodontology, 2001). During chronic inflammation, the progression of periodontal disease may affect the multirooted teeth (Sanz et al. , 2015). There are several treatment options in cases with furcation involvement. Regeneration is one of those, but it requires very careful preliminary considerations to get the expected outcomes (Bowers et al. , 2003).