When it comes to adipose stem cell therapy the market is expected to grow due to the
awareness of the role of regenerative medicine in disease treatment. The increase in
private and public funding to support stem cell-based research, in addition to the rise in
regulatory approvals for adipose stem cell clinical trials, nurtures the growth of the
adipose stem cell therapy market. On the other hand, the high cost associated to stem
cell processing and technical limitations is hindering the growth of the
market (Transparency Market Research, 2020). Regarding Adipistem, the business
primary markets are inflammatory diseases. We can see that there are some factors
regarding these diseases that increase the prevalence.
2
Figure 1: The global stem cell market (Markets&markets, 2020)
Inflammatory bowel disease
Inflammatory bowel disease includes both Crohn’s disease, which can affect any part of
the digestive tract, and ulcerative colitis, which is only found in the large intestine. Active
inflammation of the mucosa in these areas can result in reduced mucus boundaries and
ulcers (Punt et al. , 2019). IBD is increasing worldwide and is becoming a global
emergence disease. The increase is being linked to the westernized lifestyle and
other environmental factors. It has a high prevalence in North America (Punt et al. ,
2019). In addition, it is also steadily rising in developing countries due to the
rapid modernization and westernization of the population (Amosy E. M’Koma,
2013). To exemplify this; the prevalence in the United States increased from 0, 9% in
1990 to 1, 3% in 2015 (Centers for disease control and prevention, 2020).
Rhematoid arthritis is a systemic autoimmune disease that usually develops later in life,
and leads to chronic inflammation in the joints, which leads to progressive
destruction (Punt et al. , 2019). From 1990 to 2019 the annual incidence rate of
rheumatoid arthritis increased from 7, 4% to 8, 2%. The prevalence was highest in highincome
North America, Western Europe, and the Caribbean. The prevalence rate is
higher for women, and the prevalence rate is increasing with age and peaking around 74
years for men and 79 years for women (Rheumatology Advisor, 2019).
Rheumatoid arthritis
Psoriasis is a skin disorder that causes the cells in the skin to multiply faster than normal
and result in red, itchy scaly patches. The main cause of psoriasis is not known, but it is
associated with inflammation in the affected skin areas (Langeland, 2015). Danielsen
et. al performed a 30-yearlong study regarding an increase in the prevalence of
psoriasis. The study showed that between 1979 to 2008 there has been an increase
from 4, 8% to 11, 4% in self-reported lifetime prevalence of psoriasis. In 2008 there were
9, 9% who reported a doctor’s diagnosis of psoriasis in the study group. It has a high
prevalence in North America (WHO, 2016). The increase in prevalence may be linked to
changes in lifestyle, environmental factors, or an increased awareness of the
disease (Danielsen, Olsen, Wilsgaard & Furberg, 2013).
When
it
comes
to adipose
stem
cell
therapy the
market
is
expected
to grow due to the
awareness of the role of regenerative medicine in
disease
treatment. The
increase
in
private and public funding to support
stem
cell-based research,
in addition
to the rise in
regulatory approvals for adipose
stem
cell
clinical trials, nurtures the growth of the
adipose
stem
cell
therapy
market
.
On the other hand
, the high cost associated to stem
cell processing and technical limitations is hindering the growth of the
market (Transparency
Market
Research, 2020). Regarding
Adipistem
, the business
primary markets are inflammatory
diseases
. We can
see
that there are
some
factors
regarding these
diseases
that
increase
the prevalence.
2
Figure 1: The global
stem
cell
market
(
Markets&markets
, 2020)
Inflammatory bowel disease
Inflammatory bowel
disease
includes both
Crohn
’s
disease
, which can affect any part of
the digestive tract, and ulcerative colitis, which is
only
found in the large intestine. Active
inflammation of the mucosa in these areas can result in
reduced
mucus boundaries and
ulcers (Punt et al.
,
2019).
IBD
is increasing worldwide and is becoming a global
emergence
disease
. The
increase
is
being linked
to the westernized lifestyle and
other environmental factors. It has a high
prevalence
in North America (Punt et al.
,
2019).
In addition
, it is
also
steadily
rising in
developing countries
due to the
rapid modernization and
westernization
of the population (
Amosy
E. M’
Koma
,
2013). To exemplify this; the
prevalence
in the United States increased from 0, 9% in
1990 to 1, 3% in 2015 (Centers for
disease
control and prevention, 2020).
Rhematoid
arthritis is a systemic autoimmune
disease
that
usually
develops later in life,
and leads to chronic inflammation in the joints, which leads to progressive
destruction (Punt et al.
,
2019). From 1990 to 2019 the annual incidence rate of
rheumatoid arthritis increased from 7, 4% to 8, 2%. The
prevalence
was highest in
highincome
North America, Western Europe, and the Caribbean. The
prevalence
rate is
higher for women, and the
prevalence
rate is increasing with age and peaking around 74
years for
men
and 79 years for women (Rheumatology Advisor, 2019).
Rheumatoid arthritis
Psoriasis is a skin disorder that causes the
cells
in the skin to multiply faster than normal
and result in red, itchy scaly patches. The main cause of psoriasis is not known,
but
it
is
associated
with inflammation in the
affected
skin areas (
Langeland
, 2015).
Danielsen
et
.
al
performed a 30-yearlong study regarding an
increase
in the
prevalence
of
psoriasis. The study
showed
that
between 1979 to 2008
there has been an increase
from 4, 8% to 11, 4% in self-reported lifetime
prevalence
of psoriasis. In 2008 there were
9, 9% who reported a doctor’s diagnosis of psoriasis in the study group. It has a high
prevalence in North America (WHO, 2016). The
increase
in
prevalence
may
be linked
to
changes
in lifestyle, environmental factors, or an increased awareness of the
disease (
Danielsen
, Olsen,
Wilsgaard
&
Furberg
, 2013).